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Allen P Kaplan Selected Research

Bradykinin

6/2021Blood Clotting and the Pathogenesis of Types I and II Hereditary Angioedema.
2/2021Pathways for bradykinin formation and interrelationship with complement as a cause of edematous lung in COVID-19 patients.
11/2020Hereditary angioedema: Investigational therapies and future research.
1/2020Preventing anaphylaxis fatalities: Should we target bradykinin?
1/2017Pathogenesis of Hereditary Angioedema: The Role of the Bradykinin-Forming Cascade.
10/2016Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent.
6/2015In vitro comparison of bradykinin degradation by aliskiren, a renin inhibitor, and an inhibitor of angiotensin-converting enzyme.
1/2014Bradykinin-mediated diseases.
8/2013Factor XII-independent activation of the bradykinin-forming cascade: Implications for the pathogenesis of hereditary angioedema types I and II.
4/2011Bradykinin and the pathogenesis of hereditary angioedema.
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Allen P Kaplan Research Topics

Disease

23Hereditary Angioedemas
03/2022 - 01/2002
22Angioedema
02/2022 - 01/2002
20Chronic Urticaria
01/2021 - 01/2002
10Urticaria (Hives)
01/2019 - 11/2002
8Asthma (Bronchial Asthma)
09/2015 - 01/2002
5Anaphylaxis (Anaphylactic Shock)
01/2020 - 02/2002
4Hypersensitivity (Allergy)
01/2014 - 03/2002
3Inflammation (Inflammations)
11/2011 - 02/2002
3Hypertension (High Blood Pressure)
07/2011 - 02/2002
2COVID-19
02/2021 - 01/2021
2Infections
01/2021 - 07/2017
2Allergic Rhinitis
11/2017 - 02/2002
2Alzheimer Disease (Alzheimer's Disease)
01/2014 - 01/2005
2Hereditary Angioedema Types I and II
08/2013 - 06/2008
2Hyperkalemia
07/2011 - 10/2010
2Cough
10/2010 - 01/2005
2Hypotension (Low Blood Pressure)
01/2010 - 02/2002
2Pruritus (Itching)
06/2005 - 03/2002
1Thrombosis (Thrombus)
06/2021
1Severe Acute Respiratory Syndrome
01/2021
1Prekallikrein Deficiency
11/2020
1Thyroiditis
05/2018
1Neoplasms (Cancer)
11/2016
1Pheochromocytoma
01/2015
1Vasculitis (Vasculitides)
11/2012
1Cryopyrin-Associated Periodic Syndromes
08/2012
1Schnitzler Syndrome
08/2012
1Neuroblastoma
11/2010
1Neurodegenerative Diseases (Neurodegenerative Disease)
11/2010
1Down Syndrome (Down's Syndrome)
11/2010
1Chronic Pain
11/2010
1Diarrhea
10/2010

Drug/Important Bio-Agent (IBA)

22BradykininIBA
06/2021 - 01/2002
10Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
06/2015 - 01/2002
8KininsIBA
01/2021 - 09/2005
8Omalizumab (Xolair)FDA Link
01/2021 - 09/2008
6Immunoglobulin E (IgE)IBA
01/2021 - 06/2008
6Histamine Antagonists (Antihistamines)IBA
01/2021 - 11/2012
6Factor XII (Hageman Factor)IBA
11/2020 - 06/2008
6IgE Receptors (Fc epsilon RI)IBA
01/2019 - 11/2002
6Immunoglobulin G (IgG)IBA
05/2018 - 01/2002
5Complement System Proteins (Complement)IBA
02/2021 - 04/2005
5Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2010
5PrekallikreinIBA
11/2020 - 09/2008
4CytokinesIBA
07/2017 - 04/2002
4AutoantibodiesIBA
09/2008 - 11/2002
3Biological ProductsIBA
01/2021 - 08/2012
3High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA
11/2020 - 09/2008
3Factor XIIa (Coagulation Factor XIIa)IBA
11/2020 - 03/2010
3Kallikreins (Kallikrein)IBA
10/2016 - 06/2008
3Pharmaceutical PreparationsIBA
11/2011 - 06/2005
2AntigensIBA
01/2019 - 05/2018
2Interleukin-1 (Interleukin 1)IBA
07/2017 - 08/2012
2A-factor (Streptomyces)IBA
07/2017 - 01/2016
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
06/2015 - 01/2014
2Angiotensin Receptor AntagonistsIBA
06/2015 - 07/2011
2Phosphotransferases (Kinase)IBA
01/2015 - 11/2010
2neurotropinIBA
01/2015 - 11/2010
2Histamine (Histamine Dihydrochloride)FDA Link
01/2014 - 11/2002
2aliskirenFDA Link
07/2011 - 10/2010
2Renin InhibitorsIBA
07/2011 - 10/2010
2LeukotrienesIBA
06/2008 - 11/2002
2Interleukin-5 (Interleukin 5)IBA
11/2004 - 11/2002
2AllergensIBA
04/2002 - 03/2002
1Monoclonal AntibodiesIBA
02/2022
1Indicators and Reagents (Reagents)IBA
02/2022
1Peptides (Polypeptides)IBA
01/2021
1RNA (Ribonucleic Acid)IBA
11/2020
1Mannose (D-Mannose)IBA
11/2020
1EnzymesIBA
11/2020
1Serine Proteases (Serine Protease)IBA
11/2020
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
07/2017
1Estrogens (Estrogen)FDA Link
07/2017
1FibrinolysinFDA Link
07/2017
1PlasminogenIBA
07/2017
1Biomarkers (Surrogate Marker)IBA
01/2017
1PlasticsIBA
10/2016
1Plasminogen Activator Inhibitor 2IBA
01/2016
1EnalaprilFDA LinkGeneric
06/2015
1Nerve Growth Factor (NGF)IBA
01/2015
1Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA
11/2014
1Leukotriene Antagonists (Leukotriene Receptor Antagonists)IBA
05/2014
1Amyloid (Amyloid Fibrils)IBA
01/2014
1Proteoglycans (Proteoglycan)IBA
01/2014
1CryoglobulinsIBA
01/2014
1ColchicineFDA LinkGeneric
11/2012
1Cyclosporine (Ciclosporin)FDA LinkGeneric
11/2012
1DapsoneFDA Link
11/2012
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
11/2012
1Adrenal Cortex Hormones (Corticosteroids)IBA
11/2012
1Sulfasalazine (Azulfidine)FDA LinkGeneric
11/2012
1DiureticsIBA
07/2011
1Analgesics (Analgesic Drugs)IBA
11/2010
1Brain-Derived Neurotrophic Factor (BDNF)IBA
11/2010
1Plasma KallikreinIBA
03/2010
1Blood Proteins (Serum Proteins)IBA
03/2010

Therapy/Procedure

13Therapeutics
03/2022 - 03/2002
1Investigational Therapies (Experimental Therapy)
11/2020
1Intravenous Administration
01/2020
1Oral Administration
11/2010